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Asbestos-Related Pulmonary Spindle Cell Carcinoma Presenting With Ileus: An Autopsy Case Report

Year: 2025

Type: article

Abstract: We present the case of an 84-year-old male with a history of occupational asbestos exposure who initially developed ileus, which was later found to be related to an aggressive pulmonary malignancy. Imaging revealed extensive pleural thickening, peritoneal dissemination, and ileus. Postmortem examination confirmed a diagnosis of pulmonary spindle cell carcinoma (PSCC), supported by immunohistochemical analysis and the presence of numerous asbestos bodies in lung tissue. This case highlights the diagnostic complexity of rare thoracic malignancies, particularly when presenting with atypical features such as ileus. Further investigation is warranted to better understand asbestos-related carcinogenesis and to improve diagnostic and treatment approaches.

Source: Cureus

DOI: 10.7759/cureus.83634

Authors: Kohei Yamane, Shiro Moriyama, Soichiro Ishikawa, Koji Fukutani, Akira Yamasaki

Institutions: Sanin Rosai Hospital, Tottori University

Language: English

Topic: Occupational and environmental lung diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410175345