End-tidal carbon dioxide monitoring during procedural sedation: A Controlled Randomized Clinical Study.
Year: 2025
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Background: basic anaesthetic procedure performed in the morning is capnography for sedation. Objectives: assess how varying oxygen flow rates impact end-tidal carbon dioxide monitoring in patients receiving procedural sedation for small gynecological operations. Subjects: One hundred twenty patients scheduled for minor gynecological operations that required procedural sedation were included in this prospective, randomized, double-blind trial. Three groups of patients were randomly assigned. The oxygen flow rate was 4 L/min for Group A and 6 L/min for Group B. In addition, the oxygen flow rate to Group (C) was 8 L/min. In order to measure EtCO2, capnography was utilized in every group. Results: End tidal CO2 levels are similar before induction and afterward (P= 0.58). The three groups showed a notable rise in CO2 levels following induction and up until 20 minutes later (P < 0.001), which was within the normal range of end tidal CO2. After 25 minutes from induction, the three groups' end tidal CO2 levels returned to baseline and remained there until the end of the surgery (p > 0.05), suggesting that the physiological effects of anesthesia were clearly evident. Conversely, there is no statistically significant change over time in the intergroup disparities (p > 0.05). Conclusion:Patients undergoing small gynecological procedures under deep anesthesia were found to have non-invasive EtCO2 measurements taken by the laryngeal mask airway device independent of oxygen flow rate, according to the study's conclusion. Hypoventilation under sedation can be detected early using non-invasive EtCO2 monitoring.
Authors: Ibrahim Abbas Youssef, Shimaa Hassan Mohamed, Marina A. Karam Lemoun
Institutions: Minia University, Minia University Hospital
Language: English
Subfield: Anesthesiology and Pain Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410180511
