Work

Antibiotic Loaded Bone Cement in Primary Total Hip and Knee Arthroplasty

Year: 2025

Type: article

Abstract: Background Antibiotic loaded bone cement (ALBC) is currently approved by the United States Food and Drug Administration for use in revision arthroplasty for periprosthetic joint infection, but not primary arthroplasty. Still, ALBC is commonly used prophylactically in primary arthroplasty. Methods Committee statements, registry data, and clinical and basic science research on ALBC in primary hip and knee arthroplasty were reviewed. Conclusion High-level evidence is limited at the current time. Clinical trials enrolling patients at highest risk for PJI are warranted to provide guidance for appropriate use of ALBC in the primary setting.

Source: Montefiore Einstein Journal of Musculoskeletal Medicine and Surgery

DOI: 10.1177/30498929251329316

Authors: Zachary P. Berliner, David Freccero, H. John Cooper, Eric L. Smith, Michael S. Kain

Institutions: Boston Medical Center, Columbia University Irving Medical Center, New England Baptist Hospital

Language: English

Topic: Orthopedic Infections and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4410188870

FWCI: 1.727

Cites: 42

Cited by: 2

Related to: 10