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Synthesis of Ionizable Lipids for Gene Delivery to the Lung Using an Ugi Four Component Reaction

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Year: 2025
Type: article
Source: Journal of the American Chemical Society
DOI: 10.1021/jacs.5c04123
Authors: Jonas Renner, Namratha Turuvekere Vittala Murthy, Milan Gautam, Emily Bodi, Antony Jozic, Gaurav Sahay
Institutions: Oregon State University, Oregon Health & Science University
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Heart, Lung, and Blood Institute, National Cancer Institute
Awards: Mechanistic insights on structure, topology and radiation effects on RNA nanomedicines, Delivering inhalable nanoparticles containing AI-optimized CFTR mRNA with a novel microfluidic device for treatment of CF
OpenAlex ID: W4410191687
FWCI: 2.778
Cites: 35
Cited by: 11
Related to: 10
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