Year: 2025
Type: article
Abstract: In this issue of Blood, Beri et al 1 report on the impact of Babesia divergens on human red blood cells (RBCs) with hemoglobin (Hb) AA, AS, or SS.Although parasite biology is important for babesiosis, the RBC is likely to be the chief culprit of the pathophysiology of this infectious disease.The authors provide new details about how this intraerythrocytic parasite impacts RBC deformability (RBC-D), RBC sickling, and the release of extracellular vesicles (EVs) from RBCs.These new insights may explain important features of parasite infection that drive morbidity and mortality.
Source: Blood
Authors: Ryan P. Jajosky, Sean R. Stowell
Institution: Harvard University
Language: English
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4410192503