Work

Comparable gut mucosal breakdown and microbial translocation in severe COVID-19 with and without HIV infection

Year: 2025

Type: article

Abstract: In this study, we explored the link between gut impairment and severe COVID-19 in people with HIV (PWH). We compared PWH with COVID-19 to HIV-uninfected individuals hospitalized for the same condition. Despite more severe clinical symptoms in PWH, we did not observe significant differences in gut barrier dysfunction markers between the two groups. Our findings suggest a link between SARS-CoV-2 pneumonia and gut damage, independent of HIV status, warranting further investigation into its role in COVID-19 severity.

Source: AIDS

DOI: 10.1097/qad.0000000000004166

Authors: Sabrina Marozin, Valeria Bono, Martina Mazzoccoli, Matteo Augello, Roberta Rovito, Lucia Taramasso, Antonio Di Biagio, Annapaola Callegaro, Franco Maggiolo, Elisa Borghi, Camilla Tincati, Giulia Marchetti

Institutions: University of Milan, Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo, Ospedale Policlinico San Martino, University of Genoa, Ospedale Papa Giovanni XXIII

Language: English

Topic: COVID-19 Clinical Research Studies

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4410193072

FWCI:

Cites: 12

Cited by:

Related to: 10