Work

Breast mucoepidermoid carcinoma: about a case report

Year: 2025

Type: article

Abstract: INTRODUCTION AND IMPORTANCE: Breast mucoepidermoid carcinoma (MEC) is a very rare entity and usually underdiagnosed by the pathologists. CASE PRESENTATION: 54-year-old woman with a single palpable mass on the left breast with no nipple discharge. She underwent tumoretomy. Microscopic examination revealed a well circumstanced intracystic proliferation consisted of mucoid, epidermoid and intermediate cells. The tumor cells were positive for ER, PR but negative for HER2. CLINICAL DISCUSSION: Salivary glands like neoplasms are described in the breast, and only represent 0.2 % to 0.3 % of breast carcinomas. They usually fall under the triple negative breast carcinomas. However some cases were described in the literature with a luminal A profile. The grading score used in the salivary glands based on the presence or lack thereof nuclear anaplasia, necrosis, high mitotic activity and perineural or lymphovascular invasion seems more appropriate in this rare entity. CONCLUSIONS: It is crucial for pathologists to think of this type of Breast carcinomas, especially when there is mucoid, epidermoid and intermediate cells and it does not have to fall under triple negative breast carcinomas.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2025.111402

Authors: Imane Tazi, Soumaya Ech-charif, Ismail Boujida, Mouna Khmou, Youssef Mahdi, Basma El Khannoussi

Institutions: Mohammed V University, Centre Hospitalier Ibn Sina, Institut National d'Oncologie

Language: English

Topic: Salivary Gland Tumors Diagnosis and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,090