Work

How narrow is narrow QRS in premature ventricular contractions? A novel variant of SCN5A-associated MEPPC

Year: 2025

Type: article

Abstract: Gain-of-function mutations in the SCN5A gene may cause Multifocal Ectopic Purkinje-related premature Contractions (MEPPC) linked to Purkinje system hyperpolarization and dilated cardiomyopathy. [1] This case highlights the importance of genetic testing in diagnosing arrhythmias and tailoring antiarrhythmic therapy.

Source: HeartRhythm Case Reports

DOI: 10.1016/j.hrcr.2025.05.004

Authors: Oğuzhan Ekrem Turan, Sercan Karaoğlan, Ayca Aykut, Asude Durmaz, Reşit Yiğit Yiıancıoğlu, Emin Evren Özcan

Institutions: Dokuz Eylül University, Ege University

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,100