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Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus

Year: 2025

Type: article

Abstract: Herpetic meningomyelitis is an inflammation of the meninges and spinal cord caused by Herpes simplex virus type 2 (HSV-2). It typically occurs during HSV-2 reactivation, with or without immunosuppressive factors. We report a rare case of herpetic meningomyelitis in a 41-year-old HIV-positive patient, presenting with rapidly progressive ascending paraparesis. Diagnosis was confirmed by cerebrospinal fluid (CSF) multiplex PCR, revealing HSV-2, and spinal cord MRI showing central hyperintensities. The patient was treated with intravenous acyclovir and corticosteroids, leading to significant neurological recovery. This case highlights the importance of early recognition and management of this rare neurological complication of HSV-2.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.04.001

Authors: Sara Khayer, Imane Sellam, Brahim Abouhali, Mouna ELfane

Language: English

Topic: Herpesvirus Infections and Treatments

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600

OpenAlex ID: W4410198589

FWCI:

Cites: 7

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Related to: 10