Advances in the Treatment of Melanoma: Therapeutic Innovations and Clinical Results in the Fight Against Skin Cancer
Year: 2025
Type: article
Abstract: The treatment of melanoma has advanced significantly, transforming a scenario of low expectations into a model of success in precision oncology.The aim of this study is to develop a study on advances in the treatment of melanoma, identifying therapeutic innovations and clinical results in the fight against skin cancer.The methodological approach adopted in the study was a literature review, using databases of scientific articles that contributed to the theoretical basis of the work.The results indicate that immunotherapy , particularly with immune checkpoint inhibitors such as anti-CTLA-4 and anti-PD-1/PD-L1, has profoundly changed the prognosis of patients with metastatic melanoma, promoting long-lasting response rates and significantly extending overall survival in many cases.Similarly, target therapy, especially BRAF and MEK inhibitors, has proved effective in patients with specific mutations, offering a personalized and more precise approach to dealing with the disease.The conclusion is that therapeutic advances in the treatment of melanoma have had a positive and transformative impact, not only in clinical terms, but also in terms of patients' quality of life.However, the fight against skin cancer remains a constantly evolving field, requiring the continued commitment of the scientific community, health professionals and public policies.
Authors: Rafaela de Jesus Correa, Thalyssa Luciana Nascimento Pinto Canelas, Jessica Souto Pantoja Moura, Felipe Nicolau Oliveira da Costa, Cleuson Vieira Costa, Elza Cláudia Fragoso Oliveira, Maria Gabriela da Rocha Florêncio, Nathália Duarte D K Barcellos de Albuquerque, Liana Mayra Melo de Andrade, Mauro Ricardo Souza da Luz
Language: English
Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4410201088