Work

Difluoromethylation of N-Pyrazole Using 1-Chloro-1, 1-Difluoromethane Under Mild Condition

Year: 2025

Type: article

Abstract: ABSTRACT: A simple and efficient protocol for the direct Difluoromethylation of pyrazoles has been developed. The reaction makes use of commercially available and easy handling ClCHF2 as difluoromethyl source, and provides a cost-efficient and environmentally benign access to some difluoromethylated biologically relevant molecules. Keywords: Difluoromethylation Commercially feasible route, Spectral Analysis, Pyrazoles

Source: INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT

DOI: 10.55041/ijsrem47290

Author: Tushar D

Language: English

Topic: Fluorine in Organic Chemistry

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W4410208593

FWCI:

Cites: 10

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Related to: 10