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Case Report: Phosphaturic mesenchymal tumor presenting solely as knee pain without hypophosphatemia

Year: 2025

Type: article

Abstract: Phosphaturic mesenchymal tumor (PMT) is a rare tumor disease that often leads to tumor-induced osteomalacia (TIO). The typical manifestations of this disease include hypophosphatemia and osteomalacia. The main symptom in most PMT patients is diffuse pain throughout the body. However, we report a PMT patient with typical histological features but without hypophosphatemia and TIO. This patient only presented with pain in the right knee joint. At 6 months and 1 year after surgery, follow-up revealed that the patient's swelling and pain in the right knee joint had disappeared. Moreover, the imaging and biochemical examinations conducted at the local hospital showed normal results.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1597194

Authors: Qianqian Cao, Cheng Cheng, Zhipeng Dai

Institutions: Zhengzhou University, Henan Provincial People's Hospital

Language: English

Topic: Parathyroid Disorders and Treatments

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801