Work

Comprehensive relaxometric analysis of Fe( iii ) coordination polymer nanoparticles for T 1 -MRI: unravelling the impact of coating on contrast enhancement

Year: 2025

Type: article

Abstract: H NMR relaxometric properties of these nanoparticles were systematically analyzed as a function of proton Larmor frequencies and temperature, and their performance was compared with a similar system stabilized by polyvinylpyrrolidone (PVP). We aimed to determine the frequency dependence of relaxivity in Fe(iii)-based coordination polymers, and to assess the impact of coating modifications on their MRI contrast efficacy. This knowledge is crucial for the rational design of improved Fe(iii)-based nanoprobes, allowing for optimized performance in future MRI applications.

Source: Nanoscale Advances

DOI: 10.1039/d5na00250h