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Untreated arthritis urica can cause foot ulcers and amputations in patients with diabetes

Year: 2025

Type: article

Abstract: This case report describes an 88-year-old male with severe tophaceous gouty arthritis, diabetes, and kidney impairment. Over 20 years, the patient experienced recurrent gout attacks and developed tophaceous deposits, some of which ulcerated. Walking was severely impaired by foot deformities, pain, and chronic foot ulcers. Despite multiple consultations and radiological evidence of gout, no urate-lowering therapy was prescribed. Finally, microscopic analysis of foot ulcer debris identified urate crystals, confirming gout. The patient was then started on allopurinol therapy.

Source: Ugeskrift for Læger

DOI: 10.61409/v11240823

Authors: Claus Rasmussen, Jesper Walther Larsen, Peter C.W. Holm, Trine Stenbak Bisgaard, Anne Grethe Jurik

Institutions: Amager Hospital, Hvidovre Hospital, Copenhagen University Hospital, Rigshospitalet, Regionshospital Nordjylland

Language: English

Topic: Gout, Hyperuricemia, Uric Acid

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4410243024