Work

Bismuth drug eradicates multi-drug resistant Burkholderia cepacia complex via aerobic respiration

Year: 2025

Type: article

Abstract: binding and down-regulation of key proteins. Our studies highlight the great potential of bismuth drugs and/or compounds to treat multidrug-resistant Bcc infections.

Source: Chemical Science

DOI: 10.1039/d5sc02049b

Authors: Jingru Li, Haibo Wang, Peng Gao, Runming Wang, Chun-Lung Chan, Richard Yi-Tsun Kao, Hongyan Li, Hongzhe Sun

Institution: University of Hong Kong

Language: English

Topic: Burkholderia infections and melioidosis

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Research Grants Council, University Grants Committee, University of Hong Kong

Awards: G6191491703, G6441933726, Integrative metallomic approach for deciphering the role of metals in COVID-19 immunity and discovering new biomarkers, Mechanistic insights into antimicrobial activity of bismuth compounds against Burkholderia cepacia revealed by metalloproteomics approach

OpenAlex ID: W4410243047

FWCI: 4.361

Cites: 55

Cited by: 7

Related to: 10