Work

Reductive C(sp2)–C(sp3) Coupling Protocol to Enable Linker Exploration of Cereblon E3-Ligase BRD4 Proteolysis-Targeting Chimeras

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c03157

Authors: Kaitlyn Lovato, Danielle Loskot, Christine Gelin, Lu Zhu, Charu Chaudhry, Nadeem A. Vellore, Amanda Del Rosario, Taylor Courtney, Seth Miller, Ji-Hoon Cho, Harris Bell-Temin, Jennifer D. Venable, Jean-François Brazeau

Institution: Johnson & Johnson (United States)

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4410243816

FWCI: 1.768

Cites: 42

Cited by: 7

Related to: 10