Work

Diagnostic Challenges in Philadelphia Chromosome-positive B-Lymphoblastic Leukemia/Lymphoma with Persistent BCR::ABL1 Fusion after Treatment: A Pediatric Case Report

Year: 2025

Type: article

Abstract: Philadelphia chromosome-positive (Ph+) B-lymphoblastic leukemia/lymphoma (B-ALL/LBL) is an aggressive hematologic malignancy driven by the BCR::ABL1 fusion. While many cases respond well to treatment, some patients exhibit persistent BCR::ABL1 expression after therapy, presenting significant diagnostic challenges.

Source: Journal of Clinical and Translational Pathology

DOI: 10.14218/jctp.2025.00012

Authors: Qihan Guo, Wei Xie, Andrea Fuentes, Wen Shuai

Institutions: Duke University, Oregon Health & Science University, Duke Medical Center

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4410243856