Work

Comprehensive genomic profiling and expression dynamics of the HSP gene family in Cipangopaludina chinensis under temperature stress

Year: 2025

Type: article

Abstract: Heat shock proteins (HSPs) play a crucial role in the survival of organisms by facilitating their response to various stress conditions. Cipangopaludina chinensis is an important aquaculture species in China that is highly resistant to temperature changes. To better understand the adaptation mechanisms of C. chinensis to temperature fluctuations, we identified and analyzed the HSPs in C. chinensis (CchHSPs). The 36 identified CchHSPs are distributed on nine chromosomes, and the proteins they encode predominantly exhibit alpha-helix structures. In phylogenetic analyses, each HSP subfamily formed a monophyletic clade. Different CchHSPs showed specific high expression in different tissues. In addition, CchHPS70-09, CchHPS70-12, and CchHPS90-02 were identified as hub genes in the protein-protein interaction network, and the significant elevation of the expression of these genes in foot muscle under heat stress further validated their importance for the adaptation of C. chinensis to environmental stress. This study advances our understanding of the mechanisms underlying the adaptability and stress resistance conferred by the HSP gene family in C. chinensis. These insights will facilitate future efforts aimed at designing molecular markers and conducting molecular breeding programs for this economically valuable species.

Source: Genomics Communications

DOI: 10.48130/gcomm-0025-0009