Genetic characterization of pituitary neuroendocrine tumours in the maltese population
Year: 2025
Type: conference-abstract
Abstract: Pituitary neuroendocrine tumours (PitNETs) have a prevalence of 75.7/100,000 within the Maltese population. These tumours present a wide range of clinical behaviours, from hormone overproduction to local effects secondary to compression of adjacent structures, making them a significant public health concern. Despite their prevalence, the genetic factors contributing to sporadic PitNETs, which account for 95% of all cases, remain poorly understood. The primary aim of this study was to identify genetic variants associated with PitNETs in Maltese patients using germline whole exome sequencing, thereby contributing to the global understanding of the genetic aetiology of these tumours.
Source: Endocrine Abstracts
Authors: Spiteri Emma Jayne, Alison Tabone, Mark Gruppetta, Pace Nikolai Paul, Josanne Vassallo
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4410260989