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In vitro biophysical and pharmacological profiling predicts in vivo efficacy of anti-carfentanil monoclonal antibodies in mice

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Year: 2025
Type: article
Source: Biochemical and Biophysical Research Communications
DOI: 10.1016/j.bbrc.2025.151995
Authors: Brooke K. Hoppe, Robert W. Seaman Jr, Bryan Hannon, Elaine Gay, Dustin Hicks, Carly Baehr, Haydon J. Hill, Sujata G. Pandit, Austin Baldridge, Vanessa Berner, David P. AuCoin, Scott Runyon, Marco Pravetoni
Institutions: University of Washington, RTI International, University of Minnesota, University of Nevada, Reno
Language: English

Topic: Monoclonal and Polyclonal Antibodies Research
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Institute on Drug Abuse
Awards: Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trials, Antibody-based countermeasures against fentanyl and its analogues
OpenAlex ID: W4410264464
FWCI: 1.148
Cites: 43
Cited by: 2
Related to: 10
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