Year: 2025
Type: conference-paper
Abstract: Cancer is often treated by surgical intervention, in later stages needs adjuvant chemotherapy or radiation therapy. The position of cervix is easy for drug to localized delivered through the vagina, which directly targets the action site, decreasing the dosage and systemic side effects. This method is good for fertility maintenance, because it allows for the removal of smaller tumors, thereby lowering the risk of premature labour. Additionally, localized delivery post-surgery can help greatly reduce recurrence rates, providing a better fertility protecting results compared to traditional surgery. This paper summarizes the development of targeted drug delivery systems in the past five years, and the results show that targeted drug delivery can improve the therapeutic efficiency of drugs and reduce side effects by improving drug accuracy and reducing side effects. In addition, various targeting methods are discussed, including passive targeting, physical targeting, active targeting. Their respective roles in improving therapeutic effectiveness are also be discussed. There are two main problems encountered during drug delivery, one is the ability to carry enough drug to treat, this will be solved by the choice of liposomes to be used and the second is the ability to protect the successful delivery of the drug to the organ that needs to be treated, and to solve this problem will be aided by the further addition of Carbopol as well as other substances to the liposomes. the main approach used in this article is the different methods used to prepare liposomes with different substances to counteract the substances in the vagina.
Source: BIO Web of Conferences
Authors: Zhicheng Liu, Chang Liu, Jingqi Yuan
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4410309778