Primary Squamous Cell Carcinoma of Thyroid – A Case Report with Emphasis on Treatment Options and Review of Literature
Year: 2025
Type: article
Study design: Case Report
Abstract: Introduction: Primary squamous cell carcinoma of thyroid (PSCCT) is a rare entity with less than 100 cases reported in literature. It constitutes about 1% of all thyroid cancers. It has an aggressive behaviour and unfavourable prognosis. We report a rare case of PSCCT and provide a review of literature on PSCCT. Case Report: A 45 year old gentleman with hypertension as co morbid condition reported to our hospital with complaints of swelling in anterior part of the neck. He was diagnosed as a case of carcinoma of thyroid. He underwent Total Thyroidectomy under general anaesthesia. With histopathology and IHC correlation, diagnosed as PSCCT. He received adjuvant RT to tumor bed to a total dose of 60 Gray (Gy) over a period of 6 weeks. Conclusion: PSCCT is a very rare disease with very aggressive course. There is no consensus on the line of management. Lenvatinib can be tried in PSCCT as it resembles ATC.
Authors: Gautam Vedagiri Vydia, Ramanaiah K, Aravind Krishnamoorthy, Sadanand S
Institution: Cancer Institute (WIA)
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410310652