Research and Analysis on the Progress of Eucommia ulmoides in Preventing and Treating Osteoporosis
Year: 2025
Type: article
Abstract: 骨质疏松症作为一种常见的全身代谢性骨病，在我国的防治形势极为严峻。目前，西医在骨质疏松症的研究方面已取得显著进展。与此同时，随着中医日益受到重视，中医领域对该疾病的相关研究也越发丰富，中西医结合的治疗模式更是备受关注。基于现代药理学的分析研究发现，杜仲的有效成分在防治骨质疏松症方面成效显著。这些成分能够通过调节细胞相关因子，作用于成骨细胞和破骨细胞，并激活相关信号通路以发挥治疗作用。众多研究围绕多种信号通路的主要作用途径、作用机制展开了深入的理论探索。本文通过广泛查阅国内外近年来有关杜仲与骨质疏松症的相关文献，深入分析了杜仲防治骨质疏松症的有效成分、作用机理以及临床研究成果，并进行了归纳总结，期望能为杜仲在骨质疏松症研究领域提供有价值的参考。Osteoporosis, as a common systemic metabolic bone disease, poses an extremely severe situation in terms of prevention and treatment in China. Currently, Western medicine has achieved remarkable progress in the research of osteoporosis. Meanwhile, with the increasing emphasis on traditional Chinese medicine, the related research on this disease in the field of traditional Chinese medicine has become more and more abundant, and the integrated traditional Chinese and Western medicine treatment model has attracted much attention. Based on the analysis and research of modern pharmacology, it has been found that the active ingredients of Eucommia ulmoides are highly effective in the prevention and treatment of osteoporosis. These ingredients can act on osteoblasts and osteoclasts by regulating cell-related factors and activating relevant signaling pathways to exert therapeutic effects. A large number of studies have carried out in-depth theoretical explorations on the main action pathways and mechanisms of action of various signaling pathways. This paper comprehensively reviews the relevant literature on Eucommia ulmoides and osteoporosis at home and abroad in recent years, deeply analyzes the active ingredients, action mechanisms and clinical research results of Eucommia ulmoides in the prevention and treatment of osteoporosis, and provides a summary, expecting to provide valuable reference for the research of Eucommia ulmoides in the field of osteoporosis.
Source: Advances in Clinical Medicine
Author: 祎伟 赵
Institution: Xi'an Medical University
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4410325269