Work

Complex interplay of surface properties in modulating antibacterial activity of Ti50Zr alloys

Year: 2025

Type: article

Abstract: using inhibition rates and bactericidal ratios. The results showed that surface roughness and morphology significantly affected antibacterial efficiency, with the Ti50Zr NC structure exhibiting the highest inhibition rate (60%). ZnO coating further enhanced antibacterial activity, particularly with Ti50Zr NCZnO, which showed the best performance (75% inhibition). Additionally, Ti50Zr NTZnO demonstrated a significant improvement in antibacterial efficiency, with ZnO nanoparticles (10 nm) playing a key role in membrane penetration. The study also examined the impact of surface energy, wettability, and electrochemical properties on bacterial adhesion and killing mechanisms. These findings underscore the critical influence of surface nanostructuring, ZnO nanoparticle size, and coating on enhancing the antibacterial properties of Ti50Zr, highlighting the complexity of surface interactions in optimizing biomaterials for medical applications.

Source: RSC Advances

DOI: 10.1039/d5ra01182e

Authors: Alexandra Constantinescu, Camelia Ungureanu, Cristina Dumitriu, Cristian Pirvu

Institution: Universitatea Națională de Știință și Tehnologie Politehnica București

Language: English

Topic: Antimicrobial agents and applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042