Work

Comparison of broad-spectrum anti-Pseudomonal beta-lactam antibiotics versus targeted therapy for neutropenic patients with methicillin-susceptible Staphylococcus aureus bloodstream infections

Year: 2025

Type: article

Abstract: The safety of the utilization of methicillin-susceptible Staphylococcus aureus (MSSA)-targeted therapy for the treatment of MSSA bloodstream infections in the setting of neutropenia is not well studied. This single-center, retrospective cohort study of 40 patients found no significant difference in clinical outcomes between broad-spectrum anti-Pseudomonal and MSSA-targeted beta-lactam therapy.

Source: Antimicrobial Stewardship & Healthcare Epidemiology

DOI: 10.1017/ash.2025.179

Authors: Lauren C. Russell, Jeff Klaus, Miguel A. Chavez, Erik R. Dubberke, Tamara Krekel

Institutions: Barnes-Jewish Hospital, Washington University in St. Louis

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,719