Year: 2025
Type: article
Abstract: Colonization of surfaces by bacteria followed by biofilm formation is a cause of wound infections associated with the use of medical devices as stents, catheters, implants, etc. For prevention of such infections, the preparation of surfaces with antifouling, anti-adhesive and antibacterial properties is of great interest. In this context, four zwitterionic (styrenic or methacrylic) monomers bearing a pyridinium, imidazolium or ammonium cationic group linked to a sulfonate anionic group were chosen and polymerized on ceramic for implant technology. Zwitterionic polymers were successfully grafted onto zirconia pellets through surface-initiated radical polymerization with blue-light photoactivation ("grafting from"). Wettability measurements showed the formation of hydrophilic surfaces with water contact angles in the range of 35-40°. Detailed X-ray photoelectron spectroscopy analysis revealed a surface where the zirconia pellets exhibited zwitterionic polymer brushes with high coverage. The core-level spectra of C1s, N1s and S2p were separated into many components, allowing their attribution to the different atoms in the monomer unit and confirming that zwitterionic polymers were successfully grafted from zirconia surfaces.
Source: Materials
DOI: 10.3390/ma18102279
Institutions: Centre National de la Recherche Scientifique, Université de Rouen Normandie, Institut National des Sciences Appliquées Rouen Normandie, Université de Caen Normandie, Institut de Chimie Moléculaire et des Matériaux d'Orsay, École Nationale Supérieure d'Ingénieurs de Caen, Laboratoire de Cristallographie et Sciences des Matériaux
Language: English
Subfield: Surfaces, Coatings and Films
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,137
Funder: Région Normandie
OpenAlex ID: W4410369474