Indomethacin-incorporated microemulsion-laden contact lenses for improved ocular drug delivery and therapeutic efficacy
Year: 2025
Type: article
Abstract: soaking released 62.58% ± 1.56% to 97.64% ± 1.52% of the drug within the first 6 h, followed by regulated drug release for up to 28 h, maintaining clarity and drug loading. Ocular irritancy test results indicated negligible irritation, suggesting that the Me-laden lenses are a safe and effective platform to manage ocular inflammation with the controlled delivery of IND.
Source: RSC Advances
DOI: 10.1039/d5ra01046b
Authors: Kashvi Panchal, Yashkumar Patel, Harshilkumar Jani, Mittal Dalal, Vijay R. Chidrawar, Deepanjan Datta, Popat Mohite, Abhijeet Puri, Ketan Ranch, Sudarshan Singh
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,042
Funder: Chiang Mai University
OpenAlex ID: W4410369503