Work

The Effect of Sub-Minimal Inhibitory Concentrations of Daptomycin and Linezolid on Biofilm Formation of Methicillin Resistant Staphylococcus aureus Isolated from Clinical Samples

Year: 2025

Type: article

Abstract: Objectives: ) by polymerase chain reaction. Materials and Methods: MIC values were similarly detected. Before and after serial passages, the biofilm-forming abilities of MRSA isolates were examined using the microtiter plate (MTP) method. Results: genes were detected in 31 (96.9%) of 32 MRSA isolates. Conclusion: MRSA isolates exposed to sub-MICs of the antibiotics daptomycin and linezolid were observed to form biofilms at varying levels or to lose their ability to form biofilms. The induction, reduction or eradication of biofilm depended on the type of antibiotic and the MRSA isolate.

Source: Turkish Journal of Pharmaceutical Sciences

DOI: 10.4274/tjps.galenos.2025.26723

Authors: Halil BAL, Nurten ALTANLAR, Sulhiye YILDIZ

Institutions: Sivas Cumhuriyet Üniversitesi, Ankara University, Lokman Hekim Üniversitesi

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410371832