Year: 2025
Type: article
Abstract: Giving more medication to one or a few body areas than to others is a treatment strategy known as "good drug delivery," often referred to as "targeted drug delivery."There are two frequently used ways for directing drugs to a specific organ or tissue: passive targeting and active targeting.Medication is either continually delivered by drug delivery vehicles or is limited to the target region.An ideal drug delivery vehicle would be able to flow over obstacles such as the blood-brain barrier.By delivering the medicine to the targeted site of action or absorption and blocking its release at any other non-target place, "drug targeting" is a revolutionary strategy to drug delivery.The delivery mechanism is designed to contain the medication intact and undamaged until it arrives and releases at the target location.Tailored drug delivery systems provide several advantages over standard ones, including increased pharmacological activity, less adverse effects, and lower administered dosage.The main goal of targeted drug delivery systems is to only administer therapeutic medications to diseased organs while avoiding negative effects on healthy organs.When utilizing chemotherapeutic medications to treat cancer, this is very critical.A targeted drug delivery system (DDS) transports drugs to certain tissues, organs, and cells using a range of drug carriers.Inadequate bio distribution, drug agglomeration, limited solubility, lack of selectivity, controlling drug release carrier, and natural tissue damage are among the problems that it is frequently meant to alleviate.Enhancing the pharmacological and therapeutic properties of conventional drugs is another goal.In this essay, we will discuss the method of delivering medicine with specificity.
Authors: Purva Madhukar Ghumre, Shyam Suryakant Awate, Sanjay R. Arote, Mahadevan Raju Swamy, Shubhangi Pandurang Manwar, Yogesh Baban Zambare
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4410378013