Work

Central pontine and extrapontine myelinolysis presenting as subacute atypical parkinsonism in a patient with chronic alcoholism

Year: 2025

Type: article

Abstract: Central pontine and extrapontine myelinolysis are well known osmotic demyelination syndromes (ODS) that are typically associated with the rapid correction of hyponatremia, chronic alcoholism, and malnutrition. These conditions are often reported to show various brain stem signs and movement disorders. We present the case of 48-year-old man who developed extrapyramidal symptoms owing to central pontine and extrapontine myelinolysis. Magnetic resonance imaging scans showed demyelination in the central pons, bilateral basal ganglia, and thalamus. After dopamine replacement therapy, the patient’s symptoms improved significantly.

Source: Annals of Movement Disorders

DOI: 10.4103/aomd.aomd_88_24

Authors: Biruduraju Vasavi, G. Sri Ranga Lakshmi, Hemanth Kalakuntla, Sohini Ganji, Lingolu R. Neelima

Institutions: Osmania General Hospital, Osmania Medical College

Language: English

Topic: Electrolyte and hormonal disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410378563

FWCI:

Cites: 10

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Related to: 10