Work

Integrating Cellulose Nanocrystals, Antimicrobial Photodynamic Inactivation, and Poly[2-(tert-butylamino)ethyl methacrylate] into a 3D-printed Multifaceted Antimicrobial Sensor Material for Enhanced Sterilization and Wound Care Applications

Year: 2025

Type: article

Abstract: The development of sensor materials with antimicrobial properties is crucial for advancing biomedical applications, particularly in sterilization and wound care.In this study, we present a novel approach to fabricating a multifunctional sensor material by integrating cellulose nanocrystals (CNCs) with antimicrobial photodynamic inactivation (aPDI) and poly[2-(tertbutylamino)ethyl methacrylate] (PTA) within a 3D-printed composite.CNCs, known for their biocompatibility and functional surface chemistry, serve as an ideal platform for embedding antimicrobial agents.Erythrosine, a photosensitizer, is used to activate aPDI, whereas PTA provides additional antimicrobial efficacy.The sensor material's antimicrobial performance was evaluated, demonstrating the complete inactivation of Escherichia coli and Staphylococcus aureus under green and white light irradiations.The integration of CNCs with aPDI and PTA enhances the material's sensing capabilities, allowing for the real-time monitoring of microbial contamination.This composite material is a promising candidate for applications in wound care and sterilization, providing both structural support and antimicrobial functionality.

Source: Sensors and Materials

DOI: 10.18494/sam5312

Authors: Shih-Chen Shi, Yu-Chen Xu, Chih-Kuang Chen, Dieter Rahmadiawan, Bao-Tsan Ko

Institutions: National Cheng Kung University, National Sun Yat-sen University, State University of Padang, National Chung Hsing University

Language: English

Topic: Advanced Cellulose Research Studies

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $748