Work

Chemical discovery of a novel MD2/ADAM17 dual-target inhibitor as a potential therapeutic candidate for saturated fatty acid-induced myocardial inflammatory injury

Year: 2025

Type: article

Source: Metabolism

DOI: 10.1016/j.metabol.2025.156298

Authors: Xiao-dan Zhang, Yun-shan Zhong, Hao Yan, Le-hao Jin, Jing Chen, Zhong-xi Chen, Zhe-yan Zhang, Yun-jie Zhao, Jian-chang Qian

Institutions: Wenzhou Medical University, Wenzhou Seventh People's Hospital

Language: English

Topic: Cardiac Fibrosis and Remodeling

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Wenzhou Municipal Science and Technology Bureau, Natural Science Foundation of Zhejiang Province

Awards: 新型细胞色素P450 2D6（CYP2D6）变异体的功能及其酶动力学特征研究, G2730886647, G4648180838

OpenAlex ID: W4410397679

FWCI: 3.467

Cites: 69

Cited by: 5

Related to: 10