Year: 2025
Type: article
Study design: Observational Study
Abstract: Purpose of research. One of the key tasks of modern society is the prolongation of human life. It is important to understand the signs of aging of the body, especially its cardiovascular system. This will allow us to determine the most effective criteria for assessing age-related changes in the cardiovascular system. Therefore, consideration of real data on the state of the cardiovascular system of centenarians using cardiometric analysis will make it possible to take a step towards a real understanding of the prolongation of active longevity.Methods. The cardiometric method of analyzing the phases of the cardiac cycle was used, based on the mathematical model of hemodynamics by G. Dueltsev – O. Voronova, which made it possible to evaluate the dynamic characteristics of the cardiovascular system and establish criteria for maintaining normal hemodynamics. When using cardiometry in the study of centenarians, their residence in different geographical regions, as well as the different climatic conditions of these places, were taken into account.Results. Hardware and software tools for radiometric analysis of the structure of the cardiac cycle have been developed. The study examined people over the age of 90 according to indicators including metabolic and hemodynamic parameters. The imbalance of hemodynamics of the large and small circulatory circles has been established. The main reason for the change in parameters is incomplete breathing, which affects the balance of oxygen and carbon dioxide in the blood. At the same time, there was a decrease in the level of creatine phosphate in the myocardial muscles, which characterizes the energy potential of muscle contraction. This is related to changes in the state of the cardiovascular system, which are most reflected in the phase structure of the cardiac cycle in the systolic phases R-S-L-J. The real data obtained using a commercially available hemodynamic analyzer is presented.Conclusion. The paper provides a method and effective criteria for assessing age-related changes in the cardiovascular system.
Authors: N. N. Chernov, M. Y. Rudenko
Institution: Southern Federal University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4410400413