Work

Case Series: Natural History and Treatment of Thoracic Aortic Sarcoma

Year: 2025

Type: article

Abstract: Aortic sarcoma is a rare and aggressive malignancy with a poor prognosis despite surgical resection and vascular reconstruction. We present a case series of patients with thoracic aortic sarcoma, highlighting three distinct clinical scenarios: primary resection, resection following prior thoracic aortic endograft, and nonoperative management. Our findings underscore key aspects of aortic sarcoma management, including its embolic potential, diagnostic challenges, and surgical considerations, particularly when endograft explant is required. Despite limited survival, we advocate for complete resection and vascular reconstruction with adjunctive chemoradiotherapy when feasible. Multidisciplinary collaboration remains paramount to optimize postoperative outcome in this complex pathology.

Source: Journal of Surgical Oncology

DOI: 10.1002/jso.28150

Authors: Calvin L. Chao, Nicola M. Habash, Mark K. Eskandari

Institution: Northwestern University

Language: English

Topic: Cardiac tumors and thrombi

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,570