Relationship HbA1c and Coronary Artery Disease Severity in Diabetic Patients: Insights from a Gender-Based Analysis (Survey Based Study)
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Diabetes mellitus significantly increases the risk of coronary artery disease (CAD), with glycemic control playing a crucial role in disease management. Elevated HbA1c levels have been linked to increased cardiovascular complications in diabetic patients.Objectives: The purpose of this survey-based study was to investigate the relationship between diabetes patients' HbA1c levels and the severity of their coronary artery disease (CAD). Methods: The study comprised 100 diabetic patients who had been diagnosed with CAD. Recorded were demographics, HbA1c levels, and angiographic findings (such as the number of arteries affected and degree of stenosis) that indicated the severity of CAD. Regression models and correlation coefficients were among the statistical tools used to evaluate the relationship between HbA1c levels and the severity of CAD. Results: HbA1c levels and the degree of CAD in diabetic patients showed a strong positive connection (p < 0.05). There was a continuous correlation between higher HbA1c levels and more damaged arteries as well as more stenosis. Conclusion: Elevated HbA1c levels are indicative of more severe CAD in diabetic patients. Tighter glycemic control may potentially mitigate the progression and severity of CAD in this population.
Authors: Mehru-un-nisa, Fiza shahid, Jamila Ibraheem, Sangeeza safdar, Idrees Khan
Institution: Islamia University of Bahawalpur
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410407590