Wolff-Parkinson-White Syndrome in Adults: Electrocardiographic Diagnosis and Management in a Resource-Limited Setting in Kisangani, Democratic Republic of Congo (DRC)
Year: 2025
Type: article
Study design: Case Report
Abstract: Background: Wolff-Parkinson-White (WPW) syndrome, a rare but life-threatening arrhythmia, is underdiagnosed in sub-Saharan Africa due to limited healthcare resources. This case highlights the regional uniqueness of managing WPW in Kisangani, DRC, where diagnostic and therapeutic gaps exacerbate patient outcomes. Catheter ablation, the gold standard, remains inaccessible here, necessitating reliance on pharmacotherapy. Case Presentation: A 43-year-old woman presented with three days of sudden-onset palpitations. Electrocardiography (ECG) revealed a PR interval of 90 ms, QRS duration of 130 ms, and delta waves with positive polarity in leads II, III, aVF, and V4-V6. Echocardiography confirmed normal cardiac structure (left ventricular ejection fraction: 65%, left atrial diameter: 34 mm). She was treated with sustained-release flecainide (150 mg/day) and bisoprolol (5 mg/day), achieving symptom resolution within one week. Conclusion: Strengthening arrhythmia care in resource-limited settings requires training, technology transfer, and national registries. Long-term strategies must balance pharmacotherapy with advocacy for ablation access.
Authors: Issa Issa Yakusu, Malick Ndiaye, Marguerite Tening Diouf, Salvador Mingou Joseph, Sy Mbaye, Ndeye Faye, Ngor Thiam, Gora Fall, Tshilumba Kayembe, Salomon Batina Agasa, Kane Diallo Baba Nala, Abdoulgabar Souleymane Mohamed, Sow Alioune Badara, Camille Atoba Bokele, Abdoul Kane
Institution: Université de Kisangani
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4410414665
