Year: 2025
Type: article
Abstract: Gut microbiome research is one of the most groundbreaking directions in the life sciences of the 21st century, and its background involves the deep integration of medicine, microbiology, immunology and systems biology. Gut microbiome research has crossed the "correlation discovery" stage and is driving the underlying logic of treatment strategy through the integration of interdisciplinary technologies. In the next decade, microbiome medicine will form a "diagnosis-intervention-monitoring" closed loop, the core of which is dynamic precision medicine targeting the microbiome. The research of personalized nutrition and precision microbiome medicine needs to be further explored. This paper mainly analyzed the relationship between intestinal microbes and host nutrition metabolism, especially the effects of different nutrient intake on intestinal microbial composition, and how intestinal microbes affect host health through metabolic processes. It is clear how to use intestinal microbes to intervene in individual health and how to use different nutrient ratios to improve individual intestinal microbes. It provides a reference for future studies on the relationship between intestinal microbes and host nutrition metabolism and the relationship between intestinal microbial diversity and health. The study of the influence of different individual genotypes on intestinal microbiota and the detailed mechanism of the interaction between intestinal microbiota and host metabolic pathway have not been solved. Future research can focus on more human-based clinical research to apply AI to precision nutrition.
Source: Theoretical and Natural Science
Author: Yishan Ma
Institution: Shandong Agricultural University
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4410418524