Highlights of the 14th International Bordetella Symposium
Year: 2025
Type: article
Abstract: ABSTRACT Pertussis, or whooping cough, is a highly contagious and acute respiratory illness caused primarily by the gram-negative coccobacillus Bordetella pertussis . Despite near-universal vaccination, pertussis remains one of the least-controlled vaccine-preventable infectious diseases. Since 2023, pertussis incidence has been rising, and widespread pertussis outbreaks have resurged in many countries. In response to these emerging challenges, almost 300 experts from institutions across 24 countries convened at the 14th International Bordetella Symposium in Prague, Czech Republic, from 24 to 28 June 2024 to discuss pertussis epidemiology and research and strategies to mitigate the global pertussis burden. We present here the highlights of the symposium, comprising epidemiological and clinical aspects of Bordetella infections, results of clinical trials of pertussis vaccination in pregnant women and effectiveness of maternal vaccination in protecting newborn infants in Africa and Europe, the controlled human infection model (CHIM), and the latest insights into the biology, immunology, and pathogenesis of B. pertussis infection.
Source: mSphere
Institutions: Czech Academy of Sciences, Institute of Microbiology, Vanderbilt University Medical Center, Trinity College Dublin, Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de La Plata, UK Health Security Agency, University of Bath, London School of Hygiene & Tropical Medicine, Charité - Universitätsmedizin Berlin, Louisiana State University, Louisiana State University Health Sciences Center Shreveport, University of Georgia, The Ohio State University, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Purdue University West Lafayette, University of Maryland, Baltimore, Centre National de la Recherche Scientifique, Inserm, Institut Pasteur de Lille, Centre Hospitalier Universitaire de Lille, Center for Infection and Immunity of Lille
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,500
Funders: U.S. Department of Health and Human Services, Bill and Melinda Gates Foundation, Pfizer, AstraZeneca, Sanofi, Wellcome Trust, UK Research and Innovation, Novavax, Moderna, Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator, Ministerstvo Školství, Mládeže a Tělovýchovy, Akademie Věd České Republiky, Seqirus, National Institutes of Health, Mikrobiologický Ústav, Akademie Věd České Republiky, National Institute of Allergy and Infectious Diseases
Awards: 14th International Bordetella Symposium, G1310451501, Czech National Node to the European Infrastructure for Translational Medicine, G2302197805, G3576460566, G4429324995, G5007093561, G5144002884, National Institute of Virology and Bacteriology, G8801477105, An air-liquid interface system to study Bordetella pertussis interactions with respiratory epithelia
OpenAlex ID: W4410439378