Work

Unilateral pubic hair growth: a paracrine finding indicative of underlying leydig cell tumor in a prepubertal boy

Year: 2025

Type: article

Abstract: Leydig cell tumors (LCTs) are rare in children and typically present with testicular masses and signs of early puberty. We report a case of a 6-year-old boy presenting solely with precocious pubic hair growth. Ultrasound revealed a small right testicular mass and elevated serum testosterone. Intra-operatively, hair growth was more prominent on the affected hemi-scrotum. Testis-sparing surgery confirmed a benign LCT with adjacent increased spermatogenesis. This is the first known report of ipsilateral pubic hair as a presenting sign of LCT. Localized androgen excess may be an early clinical indicator to guide timely diagnosis and treatment.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2025.103071