Eye Drops to smart gels: The future of ocular drug delivery
Year: 2025
Type: article
Abstract: This review paper assesses traditional and modern methods to enhance ocular drug delivery. Various techniques available to administer drugs include topical application, intracameral injections, intravitreal injections, and subconjunctival injections. In Addition, this review discusses eye anatomy and the associated challenges with effectively delivering medications to this organ. It emphasizes recent progress in Ophthalmic drug delivery methods, such as on-situ gel systems, nanoparticles, liposomes, and dendrimers, which improve drug retention, bioavailability, and therapeutic efficacy. The article also explores potential improvements in drug delivery for treating eye disorders by utilizing nanotechnology and stimulus-responsive gels to improve patient outcomes. The goal is to achieve targeted and continuous release. Keywords: Ocular drug delivery, in-situ gel, nano formulation, prolonged release
Authors: Rajveer Bhaskar, Monika Ola, Vaishnavi Madwe, Rohini Tikhe, Arun Pawar, Shivani Khade, Sunil Shinde
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4410467696