Work

The effect of post-thaw culture duration on singleton birthweight resulting from frozen embryo transfer cycles

Year: 2024

Type: article

Abstract: Introduction: We aimed to explore the possible link between the post-thaw culture duration and singleton birthweight resulting from frozen embryo transfer (FET) cycles. Material and methods: In this retrospective study, 216 singletons were analyzed between January 2017 and December 2018 in our center. FET cycles were allocated to two main groups based on the interval between the moment of thawing and embryo transfer. The main outcome measure was the birthweight of singletons after FET. The confounding factors for singleton birthweight were evaluated using multiple linear regression analysis. Results: -scores for singletons were also not significantly different; however, the long culture transfer group had a higher proportion of small for gestational age (SGA) than the short culture transfer group. Using multiple linear regression analysis, we found that infant gender, gestational age and maternal BMI significantly affect singleton birthweight, while the duration of post-thaw culture had no effects on newborn birthweight. Conclusions: Our study suggested that post-thaw culture duration did not affect the birthweight of singleton newborns. But singleton newborns from long post-thaw culture after a hormone replacement therapy (HRT) may have a higher risk of SGA.

Source: Archives of Medical Science

DOI: 10.5114/aoms/174868

Authors: Hongliang Yi, Chengguang Sun, Zhi Yuan, HuiJia Chen, Chanyu Zhang

Institution: Second Affiliated Hospital of Chongqing Medical University

Language: English

Topic: Assisted Reproductive Technology and Twin Pregnancy

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,078