Work

Several Probes Derived from Tetraphenyl Ethene and Triphenylamine for Cu(II) and Intracellular Carbon Monoxide Sensing

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Optical detection is a promising method for Cu 2+ detection with merits, including short sensing times, low cost, sensitive response, and ease of implementation. In this work, tetraphenylethene and triphenylamine were selected as the structural cores for constructing optical probes for Cu 2+ . The tetraphenylethene and triphenylamine groups were bonded to a ═N–N═ group, forming a probe structure. Additionally, there were two −OH groups near the ═N–N═ group, offering additional recognition sites to improve the sensing selectivity. The discussion covered the geometry, electronic transitions, optophysical properties, and spectroscopic behaviors toward copper(II). It was concluded that the −OH group improved the sensing selectivity by increasing the affinity between the probe and Cu 2+ . The electron donors in these dyes compromised the sensing selectivity but decreased the emission recovery time. The optimal probe (P1) decreased its emission quantum from 7.8 to 0.2% by Cu 2+ and then recovered to 7.4% by CO within 529 s, with its emission spectrum well recovered. The emission recovery of P1 was sensitive to temperature, and a high temperature (40 °C) helped P1 emission recovery. The recognition principle was yielding a nonemissive adduct between the probe and Cu 2+ with a complexation constant of 6.25 × 10 7 L/mol. The sensing mechanism toward Cu 2+ was revealed as the combination of static and dynamic sensing with Job’s plot, lifetime comparison, 1 H NMR, and IR comparison. The other four probes, having no −OH groups, exhibited poor sensing selectivity and lower emission recovery values. Their emission recovery times were shorter than that of P1 due to the steric factor and electronic structure. The practical sensing and imaging performance of P1 was tested.

Source: ACS Omega

DOI: 10.1021/acsomega.4c10587

Authors: Yulang Fei, Ou Zhang, Kai Sun

Institutions: Nanyang Medical College, Xijing University

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,935

Funders: Key Scientific Research Project of Colleges and Universities in Henan Province, Natural Science Basic Research Program of Shaanxi Province, Henan Provincial Science and Technology Research Project