Year: 2025
Type: article
Abstract: Indonesia has abundant natural wealth. One of the endemic plants of Papua which is often used in traditional medicine is yellow rope (A. cocculus). This study aims to determine the antibacterial activity of methanol extract of yellow rope bark (A. cocculus) against P. acnes, S. aureus, and E. coli bacteria using an experimental microbiological approach in the laboratory, and the experiment model may also serve as a contextual laboratory-based learning resource in microbiology education. The antibacterial activity test was carried out using the disc diffusion method which was made in 3 concentrations, namely 5%, 10% and 15%. The results of measuring the diameter of the inhibition zone showed that each concentration was able to inhibit the growth of P. acnes bacteria with an average diameter of 2,816 mm (Weak), 6,733 mm (Medium), 9,333 mm (Medium), and control (+) clindamycin 2 μg 14,483 mm (Strong). S. aureus bacteria with an average diameter of 3.133 mm (Weak), 6.35 mm (Medium), 8.235 mm (Medium) and control (+) clindamycin 2 μg 20.97 mm (Very strong). E. coli bacteria showed an average diameter of 3.875 mm (Weak), 6.175 mm (Medium), 8.566 mm (Medium) and control (+) ciprofloxacin 5 μg 20.783 mm (very strong). This research shows that the methanol extract of yellow stem bark (A. cocculus) has antibacterial activity.
Source: Jurnal Penelitian Pendidikan IPA
Authors: Wa Ode Nurwahida, A.M. Muslihin, Lukman Hardia
Institution: Universitas Pendidikan Muhammadiyah Sorong
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4410486366