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Synthesis and Characterization of 5-(p-nitro benzyl)-2,3-dihydro-1,3,4-oxadiazole-2-one: A Possible Prosthetic Group for Indirect Radiolabeling of Carbonyl-Containing Compounds

Year: 2025

Type: article

Abstract: 5-(p-nitro benzyl)-2,3-dihydro-1,3,4-oxadiazole-2-one was prepared in a two-step process. A new β-Carboethoxy hydrazine was prepared first, and then, a new 1,3,4-oxadiazole-2-one, was prepared, both new compounds were identified by MP, IR, 1H NMR, and elemental analysis. The new 1,3,4-oxadiazole-2-one is a possible prosthetic group when iodinated, it could be approved as a method for indirect radiolabeling of carbonyl-containing compounds.

Source: European Journal of Advanced Chemistry Research

DOI: 10.24018/ejchem.2025.6.1.163

Author: Barakat Moh’d Amin Mah’d Shabsoug

Institution: Jordan University of Science and Technology

Language: English

Topic: Structural and Chemical Analysis of Organic and Inorganic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funder: Lehigh University

OpenAlex ID: W4410486935

FWCI:

Cites: 7

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Related to: 10