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Genome-based analysis for the identification of candidate genes associated with skin-photosensitization tolerance in sheep

Year: 2025
Type: article
Abstract: In ruminant livestock, skin photosensitization, caused by the ingestion of toxic plants, is relatively common and affects animal production. In this study, genotyping data from the Illumina OvineSNP50 BeadChip from two Italian local sheep breeds (Leccese and Altamurana) were used to identify putative genomic regions associated with response to skin photosensitization. We identified four genomic regions harbouring several candidate genes related to dermatitis, immune response, and coat color, that could be potentially involved in modulating photosensitization in sheep. These findings enhance our understanding of the genetic mechanisms underlying skin photosensitization in sheep and provide valuable insights into livestock adaptation to local environmental pressure.
DOI: 10.1016/j.tvjl.2025.106380
Institutions: University of Carthage, Université Tunis Carthage, Institut National de la Recherche Agronomique de Tunisie, University of Palermo, University of Sassari, University of Georgia, University of Bari Aldo Moro
Language: English
Subfield: Genetics
Open Access status: hybrid
Estimated APC paid: $3,310
OpenAlex ID: W4410487429
FWCI: 0.533
Cites: 27
Cited by: 1
Related to: 10