Work

Visible-light-initiated metal-free C sp 3 –C sp 3 to C sp 3 –N conversion in homobenzylic sulfonamides with N -iodoimides

Year: 2025

Type: article

Abstract: -diamino derivatives. The reaction exhibits a wide functional group tolerance and allows the incorporation of bioactive-derived fragments. The mechanistic insights provided by control experiments and DFT calculations suggest that an imine intermediate is formed after C-C bond cleavage.

Source: Chemical Science

DOI: 10.1039/d5sc02168e

Authors: Guillermo Morales-Ortega, Estíbaliz Merino, Javier Carreras

Institutions: Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond