A Diagnostically Challenging Case of Typical Hemolytic Uremic Syndrome Successfully Treated With Eculizumab Therapy
Year: 2025
Type: article
Study design: Case Report
Abstract: Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy that induces microvesicular injury and occlusion and often results in acute renal failure. Atypical HUS is life-threatening and often progresses to end-stage renal disease (ESRD). However, distinguishing between typical and atypical HUS can be challenging due to comorbid conditions and/or laboratory delays. We present a severe case of typical HUS involving a series of complications requiring multidisciplinary care, successfully treated with eculizumab therapy.
Source: Cureus
DOI: 10.7759/cureus.84362
Authors: Adarsh Jha, Georgette Nader, Sumugdha Rayamajhi, Muhammad Hamdan
Institutions: Michigan State University, Sparrow Health System, Sparrow Hospital
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4410508940