Work

Extra-gastrointestinal Stromal Tumor of the Urinary Bladder: A Report of a Rare Case and Literature Review

Year: 2025

Type: article

Abstract: Extra-gastrointestinal stromal tumors (eGISTs) are rare tumors that occur outside the gastrointestinal tract but share similar histological and molecular characteristics as GISTs. This report highlights an exceptionally rare case of eGISTs in the urinary bladder of a 40-year-old man who presented with painless gross total hematuria. Computed tomography (CT) revealed a solitary bladder mass, approximately 3 × 3 cm over the anterior wall, with extravesical extension into the urachal remnants. He was diagnosed with eGIST of the urinary bladder based on histopathology and immunohistochemistry after cystoscopy and transurethral resection. The patient underwent open partial cystectomy and excision of the urachus, with an uneventful recovery and no recurrence at 28 months follow-up. This case report underscores the importance of recognizing and appropriately managing bladder eGISTs.

Source: Cureus

DOI: 10.7759/cureus.84435

Authors: Swapnil S Kushwaha, Abhilash Goyal, Shikha Goja

Institutions: Safdarjang Hospital, Vardhman Mahavir Medical College & Safdarjung Hospital, Max Super Speciality Hospital, All India Institute of Medical Sciences Guwahati, All India Institute of Medical Sciences

Language: English

Topic: Gastrointestinal Tumor Research and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4410510225