Work

The underappreciated, underrecognized problem of fourth chromosome trisomy in Drosophila melanogaster stocks and a simple, general method for building diplo-4 stocks from triplo-4 stocks

Year: 2025

Type: article

Abstract: stocks. Even though the presence of an extra chromosome can confound the interpretation of experimental crosses, many Drosophila geneticists are unaware of this potential problem. Here I describe a simple method employing a mutation in a haploinsufficient gene to recognize fourth chromosome trisomy and establish disomic stocks from trisomic stocks.

Source: PubMed

DOI: 10.17912/micropub.biology.001606

Author: Kevin R. Cook

Institutions: Indiana University Bloomington, Indiana University

Language: English

Topic: Chromosomal and Genetic Variations

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: green

Funder: National Institutes of Health

Awards: G9000093867, Bloomington Drosophila Stock Center at Indiana University