Endocrine, Metabolic and Reproductive Dysfunction in Women with Polycystic Ovarian Syndrome: A Cross-Sectional Study from Saudi Arabia
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: The endocrine condition called polycystic ovarian syndrome (PCOS) consists of three distinctive features including hyperandrogenism combined with ovulatory malfunction and polycystic ovarian appearance. The endocrine and metabolic and reproductive complications of PCOS affect approximately ten percent of women within their childbearing years. Objective: PCOS patients require evaluation of their clinical features along with hormonal imbalance and metabolic abnormalities and reproductive system problems. Methods: The study involved assessing 350 women who received Rotterdam criteria diagnosis. The research analyzed hormonal results along with reproductive histories and lipid examination data through SPSS 25. Results: About three-fourths (75%) of females exhibited high testosterone while 70% revealed HOMA-IR higher than 2.5 and 80% presented abnormal menstrual rhythms. Forty percent of patients mentioned infertility as their condition while twenty percent encountered recurrent miscarriages. Research showed that metabolic syndrome affected 45% of the patient group under study. Conclusion: Women with PCOS need early recognition followed by combined medical treatments from various health professionals because this condition creates multiple medical issues.
Authors: Fahmida Khatoon, Abeer Hassan Elhaj, Tarig Hassan Elhaj, Abdelrahim Awadelkarim Abdelrahman Mohamed, Amirah Fahad Alshammeri, Hamdan Siddig Sirag Ahmed, Farida Habib Khan, Rawabi Mohammed Aljohani, Humaira Jamal, Lama Awdah Alhazimi, Reem Abdulaziz Alraidi, Raed Abea D. Alshammari, Fayez Saud Alreshidi
Institutions: University of Ha'il, Maternity and Children's Hospital
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4410512147